Publications

  1. Wang, P, Li, J, Li, T, Li, K, Ng, PC, Wang, S et al.. Molecular principles of the assembly and construction of a carboxysome shell. Sci Adv. 2024;10 (48):eadr4227. doi: 10.1126/sciadv.adr4227. PubMed PMID:39612341 PubMed Central PMC11606499.
  2. Beck, IN, Arrowsmith, TJ, Grobbelaar, MJ, Bromley, EHC, Marles-Wright, J, Blower, TR et al.. Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition. Nucleic Acids Res. 2024;52 (4):1909-1929. doi: 10.1093/nar/gkad1220. PubMed PMID:38113275 PubMed Central PMC10899793.
  3. Paloyan, A, Sargsyan, A, Karapetyan, MD, Hambardzumyan, A, Kocharov, S, Panosyan, H et al.. Structural and biochemical characterisation of the N-carbamoyl-β-alanine amidohydrolase from Rhizobium radiobacter MDC 8606. FEBS J. 2023;290 (23):5566-5580. doi: 10.1111/febs.16943. PubMed PMID:37634202 PubMed Central PMC10952681.
  4. Ashley, B, Baslé, A, Sajjad, M, El Ashram, A, Kelis, P, Marles-Wright, J et al.. Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming α-Oxoamine Synthase. ACS Sustain Chem Eng. 2023;11 (21):7997-8002. doi: 10.1021/acssuschemeng.3c00243. PubMed PMID:37266354 PubMed Central PMC10230504.
  5. Bird, JE, Marles-Wright, J, Giachino, A. A User's Guide to Golden Gate Cloning Methods and Standards. ACS Synth Biol. 2022;11 (11):3551-3563. doi: 10.1021/acssynbio.2c00355. PubMed PMID:36322003 PubMed Central PMC9680027.
  6. Heinz, V, Jäckel, W, Kaltwasser, S, Cutugno, L, Bedrunka, P, Graf, A et al.. The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism. Commun Biol. 2022;5 (1):622. doi: 10.1038/s42003-022-03548-w. PubMed PMID:35761021 PubMed Central PMC9237108.
  7. Miksys, A, Fu, L, Madej, MG, Guerreiro, DN, Kaltwasser, S, Conway, M et al.. Molecular insights into intra-complex signal transmission during stressosome activation. Commun Biol. 2022;5 (1):621. doi: 10.1038/s42003-022-03549-9. PubMed PMID:35760945 PubMed Central PMC9237128.
  8. Heaver, SL, Le, HH, Tang, P, Baslé, A, Mirretta Barone, C, Vu, DL et al.. Characterization of inositol lipid metabolism in gut-associated Bacteroidetes. Nat Microbiol. 2022;7 (7):986-1000. doi: 10.1038/s41564-022-01152-6. PubMed PMID:35725777 PubMed Central PMC9246714.
  9. Ross, J, McIver, Z, Lambert, T, Piergentili, C, Bird, JE, Gallagher, KJ et al.. Pore dynamics and asymmetric cargo loading in an encapsulin nanocompartment. Sci Adv. 2022;8 (4):eabj4461. doi: 10.1126/sciadv.abj4461. PubMed PMID:35080974 PubMed Central PMC8791618.
  10. Giachino, A, Focarelli, F, Marles-Wright, J, Waldron, KJ. Synthetic biology approaches to copper remediation: bioleaching, accumulation and recycling. FEMS Microbiol Ecol. 2021;97 (2):. doi: 10.1093/femsec/fiaa249. PubMed PMID:33501489 .
  11. Piergentili, C, Ross, J, He, D, Gallagher, KJ, Stanley, WA, Adam, L et al.. Dissecting the structural and functional roles of a putative metal entry site in encapsulated ferritins. J Biol Chem. 2020;295 (46):15511-15526. doi: 10.1074/jbc.RA120.014502. PubMed PMID:32878987 PubMed Central PMC7667983.
  12. Ross, J, Lambert, T, Piergentili, C, He, D, Waldron, KJ, Mackay, CL et al.. Mass spectrometry reveals the assembly pathway of encapsulated ferritins and highlights a dynamic ferroxidase interface. Chem Commun (Camb). 2020;56 (23):3417-3420. doi: 10.1039/c9cc08130e. PubMed PMID:32090213 .
  13. Harris, JR, Marles-Wright, J. Introduction: Protein Oligomerization and the Formation of Macromolecular Assemblies. Subcell Biochem. 2019;93 :1-22. doi: 10.1007/978-3-030-28151-9_1. PubMed PMID:31939147 .
  14. Wichmann, L, Dulai, JS, Marles-Wright, J, Maxeiner, S, Szczesniak, PP, Manzini, I et al.. An extracellular acidic cleft confers profound H+-sensitivity to epithelial sodium channels containing the δ-subunit in Xenopus laevis. J Biol Chem. 2019;294 (33):12507-12520. doi: 10.1074/jbc.RA119.008255. PubMed PMID:31248986 PubMed Central PMC6699844.
  15. He, D, Piergentili, C, Ross, J, Tarrant, E, Tuck, LR, Mackay, CL et al.. Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea. Biochem J. 2019;476 (6):975-989. doi: 10.1042/BCJ20180922. PubMed PMID:30837306 .
  16. Liu, W, Luo, Z, Wang, Y, Pham, NT, Tuck, L, Pérez-Pi, I et al.. Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods. Nat Commun. 2018;9 (1):1936. doi: 10.1038/s41467-018-04254-0. PubMed PMID:29789543 PubMed Central PMC5964202.
  17. Ekström, AG, Kelly, V, Marles-Wright, J, Cockroft, SL, Campopiano, DJ. Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45). Org Biomol Chem. 2017;15 (30):6310-6313. doi: 10.1039/c7ob01396e. PubMed PMID:28715001 PubMed Central PMC5708339.
  18. Pané-Farré, J, Quin, MB, Lewis, RJ, Marles-Wright, J. Structure and Function of the Stressosome Signalling Hub. Subcell Biochem. 2017;83 :1-41. doi: 10.1007/978-3-319-46503-6_1. PubMed PMID:28271471 .
  19. Jensen, MV, Horsfall, LE, Wardrope, C, Togneri, PD, Marles-Wright, J, Rosser, SJ et al.. Characterisation of a New Family of Carboxyl Esterases with an OsmC Domain. PLoS One. 2016;11 (11):e0166128. doi: 10.1371/journal.pone.0166128. PubMed PMID:27851780 PubMed Central PMC5113044.
  20. McLean, CJ, Marles-Wright, J, Custodio, R, Lowther, J, Kennedy, AJ, Pollock, J et al.. Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei. J Lipid Res. 2017;58 (1):137-150. doi: 10.1194/jlr.M071258. PubMed PMID:27784725 PubMed Central PMC5234717.
  21. He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E et al.. Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. Elife. 2016;5 :. doi: 10.7554/eLife.18972. PubMed PMID:27529188 PubMed Central PMC5012862.
  22. Tuck, LR, Altenbach, K, Ang, TF, Crawshaw, AD, Campopiano, DJ, Clarke, DJ et al.. Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans. Sci Rep. 2016;6 :22108. doi: 10.1038/srep22108. PubMed PMID:26899032 PubMed Central PMC4762007.
  23. Wallock-Richards, DJ, Marles-Wright, J, Clarke, DJ, Maitra, A, Dodds, M, Hanley, B et al.. Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone. Chem Commun (Camb). 2015;51 (52):10483-5. doi: 10.1039/c5cc01816a. PubMed PMID:26029850 .
  24. He, D, Marles-Wright, J. Ferritin family proteins and their use in bionanotechnology. N Biotechnol. 2015;32 (6):651-7. doi: 10.1016/j.nbt.2014.12.006. PubMed PMID:25573765 PubMed Central PMC4571993.
  25. Müller, M, Reiß, S, Schlüter, R, Mäder, U, Beyer, A, Reiß, W et al.. Deletion of membrane-associated Asp23 leads to upregulation of cell wall stress genes in Staphylococcus aureus. Mol Microbiol. 2014;93 (6):1259-68. doi: 10.1111/mmi.12733. PubMed PMID:25074408 .
  26. Liebal, UW, Millat, T, Marles-Wright, J, Lewis, RJ, Wolkenhauer, O. Simulations of stressosome activation emphasize allosteric interactions between RsbR and RsbT. BMC Syst Biol. 2013;7 :3. doi: 10.1186/1752-0509-7-3. PubMed PMID:23320651 PubMed Central PMC3556497.
  27. Pitts, AC, Tuck, LR, Faulds-Pain, A, Lewis, RJ, Marles-Wright, J. Structural insight into the Clostridium difficile ethanolamine utilisation microcompartment. PLoS One. 2012;7 (10):e48360. doi: 10.1371/journal.pone.0048360. PubMed PMID:23144756 PubMed Central PMC3483176.
  28. McKee, LS, Peña, MJ, Rogowski, A, Jackson, A, Lewis, RJ, York, WS et al.. Introducing endo-xylanase activity into an exo-acting arabinofuranosidase that targets side chains. Proc Natl Acad Sci U S A. 2012;109 (17):6537-42. doi: 10.1073/pnas.1117686109. PubMed PMID:22492980 PubMed Central PMC3340039.
  29. Pagett, HE, Abrahams, JL, Bones, J, O'Donoghue, N, Marles-Wright, J, Lewis, RJ et al.. Structural characterisation of the N-glycan moiety of the barnacle settlement-inducing protein complex (SIPC). J Exp Biol. 2012;215 (Pt 7):1192-8. doi: 10.1242/jeb.063503. PubMed PMID:22399665 .
  30. Quin, MB, Berrisford, JM, Newman, JA, Baslé, A, Lewis, RJ, Marles-Wright, J et al.. The bacterial stressosome: a modular system that has been adapted to control secondary messenger signaling. Structure. 2012;20 (2):350-63. doi: 10.1016/j.str.2012.01.003. PubMed PMID:22325782 .
  31. Kawai, Y, Marles-Wright, J, Cleverley, RM, Emmins, R, Ishikawa, S, Kuwano, M et al.. A widespread family of bacterial cell wall assembly proteins. EMBO J. 2011;30 (24):4931-41. doi: 10.1038/emboj.2011.358. PubMed PMID:21964069 PubMed Central PMC3243631.
  32. Marles-Wright, J, Lewis, RJ. The structure of a D-lyxose isomerase from the σB regulon of Bacillus subtilis. Proteins. 2011;79 (6):2015-9. doi: 10.1002/prot.23028. PubMed PMID:21520290 .
  33. Cartmell, A, McKee, LS, Peña, MJ, Larsbrink, J, Brumer, H, Kaneko, S et al.. The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases. J Biol Chem. 2011;286 (17):15483-95. doi: 10.1074/jbc.M110.215962. PubMed PMID:21339299 PubMed Central PMC3083193.
  34. Marles-Wright, J, Lewis, RJ. The stressosome: molecular architecture of a signalling hub. Biochem Soc Trans. 2010;38 (4):928-33. doi: 10.1042/BST0380928. PubMed PMID:20658979 .
  35. Marles-Wright, J, Lewis, RJ. The Bacillus subtilis stressosome: A signal integration and transduction hub. Commun Integr Biol. 2008;1 (2):182-4. doi: 10.4161/cib.1.2.7225. PubMed PMID:19704888 PubMed Central PMC2686017.
  36. Yang, X, Molimau, S, Doherty, GP, Johnston, EB, Marles-Wright, J, Rothnagel, R et al.. The structure of bacterial RNA polymerase in complex with the essential transcription elongation factor NusA. EMBO Rep. 2009;10 (9):997-1002. doi: 10.1038/embor.2009.155. PubMed PMID:19680289 PubMed Central PMC2750059.
  37. Schirner, K, Marles-Wright, J, Lewis, RJ, Errington, J. Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis. EMBO J. 2009;28 (7):830-42. doi: 10.1038/emboj.2009.25. PubMed PMID:19229300 PubMed Central PMC2670855.
  38. Baur, S, Marles-Wright, J, Buckenmaier, S, Lewis, RJ, Vollmer, W. Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae. J Bacteriol. 2009;191 (4):1200-10. doi: 10.1128/JB.01120-08. PubMed PMID:19074383 PubMed Central PMC2631998.
  39. Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, SJ, Lewis, PJ et al.. Molecular architecture of the "stressosome," a signal integration and transduction hub. Science. 2008;322 (5898):92-6. doi: 10.1126/science.1159572. PubMed PMID:18832644 .
  40. Quin, M, Newman, J, Firbank, S, Lewis, RJ, Marles-Wright, J. Crystallization and preliminary X-ray analysis of RsbS from Moorella thermoacetica at 2.5 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008;64 (Pt 3):196-9. doi: 10.1107/S1744309108003849. PubMed PMID:18323607 PubMed Central PMC2374149.
  41. Marles-Wright, J, Lewis, RJ. Stress responses of bacteria. Curr Opin Struct Biol. 2007;17 (6):755-60. doi: 10.1016/j.sbi.2007.08.004. PubMed PMID:17920859 .
  42. Schneider, S, Marles-Wright, J, Sharp, KH, Paoli, M. Diversity and conservation of interactions for binding heme in b-type heme proteins. Nat Prod Rep. 2007;24 (3):621-30. doi: 10.1039/b604186h. PubMed PMID:17534534 .
  43. Hardwick, SW, Pané-Farré, J, Delumeau, O, Marles-Wright, J, Murray, JW, Hecker, M et al.. Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis. J Biol Chem. 2007;282 (15):11562-72. doi: 10.1074/jbc.M609733200. PubMed PMID:17303566 .
  44. Gadola, SD, Koch, M, Marles-Wright, J, Lissin, NM, Shepherd, D, Matulis, G et al.. Structure and binding kinetics of three different human CD1d-alpha-galactosylceramide-specific T cell receptors. J Exp Med. 2006;203 (3):699-710. doi: 10.1084/jem.20052369. PubMed PMID:16520393 PubMed Central PMC2118257.
  45. Paoli, M, Marles-Wright, J, Smith, A. Structure-function relationships in heme-proteins. DNA Cell Biol. 2002;21 (4):271-80. doi: 10.1089/104454902753759690. PubMed PMID:12042067 .
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